Vibroacoustic music therapy for postoperative delirium in the ICU: the VIMUD-ICU single-center exploratory randomized controlled trial - Takeaways - MDSpire
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Vibroacoustic Music Therapy for Postoperative Delirium in Intensive Care: A Single-Center Exploratory Randomized Controlled Trial (VIMUD-ICU)

  • By

  • Petra Burzlaff

  • Philipp Simon

  • Peter Michael von der Nahmer

  • Susanne Metzner

  • Philipp Deetjen

  • November 5, 2026

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  • 1

    VIMUD-ICU was a single-center exploratory randomized trial of therapist-guided vibroacoustic music therapy in nonventilated adults with postoperative delirium.

  • 2

    Among 111 randomized patients, 56 received music therapy and 55 received standard care; enrollment ended early, below the planned 122 patients.

  • 3

    The primary endpoint, time from enrollment to 48 consecutive hours without a positive delirium score, did not differ significantly between groups.

  • 4

    Secondary analyses found more delirium-free time during the delirium episode, more days free from alpha-2 agonists, and differences in arousal measures with music therapy.

  • 5

    The single-center, unmasked trial had unmatched therapist contact, and the authors characterized its secondary findings as hypothesis-generating.

Original Source(s)

Vibroacoustic music therapy for postoperative delirium in the ICU: the VIMUD-ICU single-center exploratory randomized controlled trial

  • by Petra Burzlaff, Philipp Simon, Peter Michael von der Nahmer, Susanne Metzner, Philipp Deetjen

  • November 5, 2026

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