The Effects of Gastroesophageal Reflux Disease in East Asia and China from 1990 to 2021: Findings from the 2021 Global Burden of Disease Study - Takeaways - MDSpire

The Effects of Gastroesophageal Reflux Disease in East Asia and China from 1990 to 2021: Findings from the 2021 Global Burden of Disease Study

  • By

  • Chengying Zhu

  • Zeming Le

  • Zhanjun Lu

  • Zihao Guo

  • Guo Yu

  • Zhiyuan Cheng

  • Changjie Zhao

  • Rong Wan

  • Weiliang Jiang

  • Wenqin Xiao

  • January 31, 2026

  • 0 min

Share

  • 1

    Gastroesophageal reflux disease (GERD) is increasingly prevalent in East Asia, significantly impacting quality of life and contributing to disease burden.

  • 2

    China accounted for 32,387,866 new GERD cases in 2021, representing 12.24% of the global total, with a 55.24% increase in new cases from 1990 to 2021.

  • 3

    The study utilized data from the GBD 2021 database, analyzing incidence, disability-adjusted life years (DALYs), and prevalence across East Asian countries.

  • 4

    Socioeconomic factors, including the Socioeconomic Development Index (SDI), were correlated with the burden of GERD, indicating regional disparities.

  • 5

    The findings highlight the need for region-specific clinical management and public health interventions to address the growing GERD burden in East Asia.

Original Source(s)

The Effects of Gastroesophageal Reflux Disease in East Asia and China from 1990 to 2021: Findings from the 2021 Global Burden of Disease Study

  • by Chengying Zhu, Zeming Le, Zhanjun Lu, Zihao Guo, Guo Yu, Zhiyuan Cheng, Changjie Zhao, Rong Wan, Weiliang Jiang, Wenqin Xiao

  • January 31, 2026

Related Content

Identifying Risk Factors and Developing a Predictive Model for Submucosal Invasion in Early Protruding-Type Esophagogastric Junction Adenocarcinoma: Integrating Conventional Endoscopy with Endoscopic Ultrasonography

Substance P-Related Neuro-Immune-Epithelial Interactions May Play a Role in Mucosal Damage in Gastro-Oesophageal Reflux Disease

Assessing the Effects of Ring Augmentation on Sleeve Gastrectomy Outcomes: A Retrospective Propensity-Weighted Analysis