Recurrent Gonococcemia Reveiling X-linked Properdin Deficiency: A Novel Case Report

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The patient was diagnosed with X-linked properdin deficiency after two episodes of disseminated gonococcal infections.
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Properdin deficiency is typically associated with meningococcemia but has not been previously linked to disseminated gonococcal infections.
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The patient's recurrent gonococcal infections prompted an investigation into immune deficiencies, revealing low properdin levels.
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Vaccination against meningococcal and pneumococcal diseases was initiated following the diagnosis of properdin deficiency.
5

This case highlights the need for thorough investigation of complement deficiencies in patients with recurrent gonococcal infections.

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