Evaluating negative-pressure wound therapy after abdominoperineal resection: a systematic review of efficacy and technical variability - Takeaways - MDSpire

Evaluating negative-pressure wound therapy after abdominoperineal resection: a systematic review of efficacy and technical variability

  • By

  • A. Litchinko

  • F. Ris

  • B. Noiret

  • M. Adamina

  • Q. Denost

  • September 23, 2025

  • 0 min

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  • 1

    Abdominoperineal resection (APR) is the standard surgical approach for low rectal cancer, associated with significant postoperative morbidity.

  • 2

    Perineal wound complications after APR can occur in up to 50% of patients, impacting recovery and quality of life.

  • 3

    Negative pressure wound therapy (NPWT) is increasingly used to manage perineal wounds post-APR, promoting healing and reducing complications.

  • 4

    Prophylactic NPWT has shown promise in lowering surgical site infections, but evidence regarding its long-term efficacy remains limited.

  • 5

    Further research is needed to establish optimal NPWT application strategies and to identify patient populations that may benefit most.

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