Evaluating negative-pressure wound therapy after abdominoperineal resection: a systematic review of efficacy and technical variability - Takeaways - MDSpire

Assessing the Effectiveness and Technical Variability of Negative-Pressure Wound Therapy Following Abdominoperineal Resection: A Systematic Review

By
A. Litchinko
F. Ris
B. Noiret
M. Adamina
Q. Denost
September 23, 2025

Techniques In Coloproctology

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1

Abdominoperineal resection (APR) is the standard surgical approach for low rectal cancer, associated with significant postoperative morbidity.
2

Perineal wound complications after APR can occur in up to 50% of patients, impacting recovery and quality of life.
3

Negative pressure wound therapy (NPWT) is increasingly used to manage perineal wounds post-APR, promoting healing and reducing complications.
4

Prophylactic NPWT has shown promise in lowering surgical site infections, but evidence regarding its long-term efficacy remains limited.
5

Further research is needed to establish optimal NPWT application strategies and to identify patient populations that may benefit most.

Original Source(s)

Techniques In Coloproctology

Evaluating negative-pressure wound therapy after abdominoperineal resection: a systematic review of efficacy and technical variability

by A. Litchinko, F. Ris, B. Noiret, M. Adamina, Q. Denost
September 23, 2025

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