A risk-scoring model for predicting late postoperative hemorrhage following pancreatoduodenectomy: development and external validation - Takeaways - MDSpire

A risk-scoring model for predicting late postoperative hemorrhage following pancreatoduodenectomy: development and external validation

  • By

  • Shuai Xu

  • Qi Zhang

  • Liping Zang

  • Yuxiao Zhang

  • Jun Liu

  • Juan Zhang

  • Jianping Wang

  • July 6, 2026

  • 0 min

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  • 1

    A risk-scoring model for predicting late post-pancreatectomy hemorrhage (PPH) was developed and validated using clinical data from 405 patients.

  • 2

    Late PPH occurred in 7.7% of the training cohort and 7.6% of the validation cohort, significantly affecting long-term survival.

  • 3

    Independent risk factors for late PPH identified were body mass index, preoperative total bilirubin, prothrombin time, and clinically relevant postoperative pancreatic fistula.

  • 4

    The predictive model achieved concordance indices of 0.863 in the training cohort and 0.825 in the validation cohort.

  • 5

    Patients were stratified into low-risk and high-risk groups based on the scoring model to facilitate targeted monitoring and prevention.

Original Source(s)

A risk-scoring model for predicting late postoperative hemorrhage following pancreatoduodenectomy: development and external validation

  • by Shuai Xu, Qi Zhang, Liping Zang, Yuxiao Zhang, Jun Liu, Juan Zhang, Jianping Wang

  • July 6, 2026

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