Predicting preoperative axillary lymph node metastasis to guide surgical decisions in invasive breast cancer - Takeaways - MDSpire

Predicting preoperative axillary lymph node metastasis to guide surgical decisions in invasive breast cancer

  • By

  • Qi Xin

  • Zhilin Yang

  • May 29, 2026

  • 0 min

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  • 1

    The study analyzed clinical data from 454 invasive breast cancer patients to predict axillary lymph node metastasis (ALNM).

  • 2

    A nomogram was developed using clinicopathological, ultrasound, and serological indicators to enhance ALNM prediction accuracy.

  • 3

    Independent risk factors for ALNM included tumor size, circumscribe margin, ultrasonic lymph node status, WBC, ER, and BI-RADS.

  • 4

    The nomogram showed modest predictive performance with AUCs of 0.741 in the training group and 0.705 in the validation group.

  • 5

    The model supports preoperative risk stratification but cannot replace standard axillary staging procedures like sentinel lymph node biopsy.

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