Epithelial cell proliferation on anterior surface of intraocular lens after Descemet stripping automated endothelial keratoplasty (DSAEK) surgery: a case report - Takeaways - MDSpire

Epithelial cell proliferation on anterior surface of intraocular lens after Descemet stripping automated endothelial keratoplasty (DSAEK) surgery: a case report

  • By

  • Ali Zare

  • Mozhgan Rezaei Kanavi

  • Sepehr Feizi

  • Fariba Pirsarabi

  • Faezeh Tajari

  • June 17, 2026

  • 0 min

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  • 1

    Intraocular lens (IOL) opacification can lead to glare, reduced contrast sensitivity, and decreased visual acuity.

  • 2

    Epithelial cell proliferation on IOL surfaces is a rare cause of opacification, potentially linked to intraoperative trauma and chronic inflammation.

  • 3

    A case study describes a 61-year-old woman with progressive visual decline due to epithelial cell proliferation on her IOL after DSAEK.

  • 4

    Histopathological evaluation confirmed epithelial cell proliferation on the IOL surface, with no calcium deposits detected.

  • 5

    IOL opacification incidence is reported at 5%-9.7% following DSAEK, primarily affecting hydrophilic acrylic IOLs.

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