Baseline working memory was associated with improvement in psychological quality of life in patients with persistent depressive symptoms: a prospective observational study - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Initial working memory levels correlated with enhancements in psychological quality of life among individuals experiencing ongoing depressive symptoms: a prospective observational analysis

  • By

  • Yuki Oe

  • Mariko Kurihara

  • Tomonari Hayasaka

  • Izumi Nagashima

  • Masami Murao

  • Yasuyuki Matsumoto

  • Yoshikazu Takaesu

  • Takashi Tsuboi

  • Koichiro Watanabe

  • Hitoshi Sakurai

  • May 21, 2026

Share

  • 1

    Cognitive dysfunction significantly affects quality of life and functional outcomes in patients with persistent depressive symptoms.

  • 2

    Higher baseline working memory is linked to greater improvement in psychological quality of life over six months.

  • 3

    No significant overall improvement in quality of life or functioning was observed in the study cohort over six months.

  • 4

    The study included 84 patients with persistent depressive symptoms, assessing cognitive function and quality of life at multiple time points.

  • 5

    Findings suggest working memory may serve as a prognostic marker for psychological well-being in patients with persistent depressive symptoms.

Original Source(s)

Baseline working memory was associated with improvement in psychological quality of life in patients with persistent depressive symptoms: a prospective observational study

  • by Yuki Oe, Mariko Kurihara, Tomonari Hayasaka, Izumi Nagashima, Masami Murao, Yasuyuki Matsumoto, Yoshikazu Takaesu, Takashi Tsuboi, Koichiro Watanabe, Hitoshi Sakurai

  • May 21, 2026

Related Content

Sodium-Glucose Cotransporter 2 Inhibitors and Dementia Risk in Patients With Psychiatric Disorders

Editorial: Loneliness among youth and young adults

Detecting bipolarity using the Lebanese Arabic hypomania checklist (HCL-32): validation of shortened HCL versions