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Why Early NK Treatment Matters

Recognizing the importance of early treatment strategies in neurotrophic keratitis

  • By

  • Sean Cushman

  • March 2, 2026

  • 6 min

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  • 1

    Neurotrophic keratitis (NK) can lead to severe visual impairment if not diagnosed and treated early.

  • 2

    The Mackie classification system stages NK from punctate keratopathy to corneal ulceration and perforation.

  • 3

    Cryopreserved amniotic membrane (CAM) is the first-line therapy for early NK, promoting nerve regeneration.

  • 4

    Cenegermin, a nerve growth factor, is effective for advanced NK but may face insurance authorization delays.

  • 5

    Long-term management of NK requires patient education, adherence to treatment, and addressing underlying conditions.

Original Source(s)

Why Early NK Treatment Matters

  • by Sean Cushman

  • March 2, 2026

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