Assessment of the Frequency of Psychological Comorbidities and Their Impact on Injection Therapy Results in Individuals with Chronic Low Back Pain: A Retrospective Cohort Analysis Using Registry Data - Takeaways - MDSpire

Assessment of the Frequency of Psychological Comorbidities and Their Impact on Injection Therapy Results in Individuals with Chronic Low Back Pain: A Retrospective Cohort Analysis Using Registry Data

  • By

  • Anas Afifi

  • Khaled Allan

  • Marc Brügmann

  • Andrea Roth-Daniek

  • Rolf Sobottke

  • Moh’d Yazan Khasawneh

  • Koroush Kabir

  • Alba Shehu

  • Michel Teuben

  • Ümit Mert

  • Maher Ghandour

  • Mohamad Agha Mahmoud

  • April 28, 2026

  • 0 min

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  • 1

    Psychological comorbidities, including depression and anxiety, are prevalent in patients with chronic low back pain (CLBP) and radicular pain (RP).

  • 2

    Depression was found in 37.6% of patients, while anxiety and stress symptoms were present in 28-31% and 45%, respectively.

  • 3

    Patients with psychological comorbidities reported higher pain severity before treatment and experienced less pain reduction after injection therapy.

  • 4

    For instance, patients with depression had higher baseline pain scores (8.15) compared to those without (7.24) and lower post-treatment scores.

  • 5

    The study highlights the need for integrating psychological assessment and intervention in the multidisciplinary management of CLBP.

Original Source(s)

Assessment of the Frequency of Psychological Comorbidities and Their Impact on Injection Therapy Results in Individuals with Chronic Low Back Pain: A Retrospective Cohort Analysis Using Registry Data

  • by Anas Afifi, Khaled Allan, Marc Brügmann, Andrea Roth-Daniek, Rolf Sobottke, Moh’d Yazan Khasawneh, Koroush Kabir, Alba Shehu, Michel Teuben, Ümit Mert, Maher Ghandour, Mohamad Agha Mahmoud

  • April 28, 2026

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