Acupuncture effects on non-motor symptoms of Parkinson’s disease (sleep, mood, and fatigue): a systematic review and meta-analysis - Takeaways - MDSpire

Acupuncture effects on non-motor symptoms of Parkinson’s disease (sleep, mood, and fatigue): a systematic review and meta-analysis

  • By

  • Yizhi Cui

  • Ruidong Xue

  • Bo Zhang

  • Hong Huo

  • Qianshi Zhang

  • Bingjie Gao

  • Yanpei Zhao

  • Shenglun Mao

  • Weibo Zhong

  • Jiaqi Zhao

  • May 7, 2026

  • 0 min

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  • 1

    Acupuncture shows moderate-certainty evidence for improving sleep quality in Parkinson's disease, as indicated by enhanced PDSS scores.

  • 2

    Anxiety reduction from acupuncture is supported by a single RCT, showing a significant decrease in HAM-A scores at follow-up.

  • 3

    Fatigue outcomes from acupuncture lack sufficient evidence, with no significant difference observed compared to sham treatments.

  • 4

    The review included eight studies, comprising four RCTs and four observational studies, focusing on specific non-motor symptoms.

  • 5

    Further multicenter RCTs with standardized methodologies and longer follow-up periods are necessary to validate these findings.

Original Source(s)

Acupuncture effects on non-motor symptoms of Parkinson’s disease (sleep, mood, and fatigue): a systematic review and meta-analysis

  • by Yizhi Cui, Ruidong Xue, Bo Zhang, Hong Huo, Qianshi Zhang, Bingjie Gao, Yanpei Zhao, Shenglun Mao, Weibo Zhong, Jiaqi Zhao

  • May 7, 2026

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