Tricuspid regurgitation thresholds reassessed

The proposed framework classified 30% of patients as high or extreme risk, compared with 12% classified as having severe or greater tricuspid regurgitation under established grading schemes.

By
Kathryn Wighton
September 9, 2026
4 min

MDSpire News

1

A study published in JAMA Cardiology assessed tricuspid regurgitation thresholds in patients with transthyretin amyloid cardiomyopathy.
2

The study included 1,124 patients, with a median age of 80 years, and excluded those with prior tricuspid valve interventions.
3

New disease-specific echocardiographic thresholds for tricuspid regurgitation showed better prognostic discrimination than existing guidelines.
4

The proposed thresholds for tricuspid regurgitation were significantly lower than conventional cutoffs in current guidelines.
5

The framework demonstrated greater discrimination for mortality and heart failure hospitalization compared to existing guideline definitions.

Tricuspid regurgitation thresholds reassessed

1

2

3

4

5

Original Source(s)

Tricuspid regurgitation thresholds reassessed

Related Content

In vivo coronary stent evaluation using photon-counting computed tomography: diagnostic performance

Echocardiography-derived hemodynamic forces in cardiac resynchronization therapy: association with reverse remodeling and long-term outcomes

Sodium Thiosulfate for Refractory Metabolic Alkalosis From Diuretic Therapy: A Case Series of Six Patients