Elevated serum uric acid increases incident coronary artery calcification risk in Chinese adults undergoing health checkups - Takeaways - MDSpire

Elevated serum uric acid increases incident coronary artery calcification risk in Chinese adults undergoing health checkups

  • By

  • You You

  • Qixiang Lei

  • Min Ni

  • Ke Ming

  • Yujun Long

  • Yu Lu

  • July 15, 2026

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  • 1

    The study included 6,996 participants without coronary artery calcification at baseline, followed for a median of 6.0 years.

  • 2

    560 participants (8.0%) developed incident coronary artery calcification during the follow-up period.

  • 3

    Each standard deviation increase in serum uric acid was associated with a higher risk of incident coronary artery calcification (HR: 1.21, P < 0.001).

  • 4

    Participants with hyperuricemia had a significantly higher risk of incident coronary artery calcification compared to those with normal uric acid levels (HR: 1.31, P = 0.005).

  • 5

    A linear dose–response association was observed between serum uric acid levels and the risk of incident coronary artery calcification.

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