Textbook oncologic outcomes in elderly patients undergoing neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer: a multicenter study - Takeaways - MDSpire

Textbook oncologic outcomes in elderly patients undergoing neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer: a multicenter study

  • By

  • Alessandra Pulvirenti

  • Carlotta Parati

  • Simona Deidda

  • Daniela Rega

  • Gino Guarino

  • Mirko Armas

  • Ilaria Govoni

  • Silvia Negro

  • Quoc Riccardo Bao

  • Paolo Delrio

  • Angelo Restivo

  • Gaya Spolverato

  • August 25, 2025

  • 0 min

Share

  • 1

    Colorectal cancer is increasingly diagnosed in elderly patients, with over half of cases occurring in those aged 70 and older.

  • 2

    Neoadjuvant chemoradiotherapy followed by total mesorectal excision is the standard treatment for locally advanced rectal cancer.

  • 3

    Textbook Oncologic Outcome (TOO) is a composite quality metric that assesses surgical and oncologic treatment quality.

  • 4

    The study included 157 elderly patients with locally advanced rectal cancer who underwent surgery after neoadjuvant treatment.

  • 5

    Achieving TOO is crucial for optimizing oncologic care and improving surgical outcomes in elderly rectal cancer patients.

Original Source(s)

Textbook oncologic outcomes in elderly patients undergoing neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer: a multicenter study

  • by Alessandra Pulvirenti, Carlotta Parati, Simona Deidda, Daniela Rega, Gino Guarino, Mirko Armas, Ilaria Govoni, Silvia Negro, Quoc Riccardo Bao, Paolo Delrio, Angelo Restivo, Gaya Spolverato

  • August 25, 2025

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