Case Report: HIT-related valve thrombosis in an LVAD patient - Takeaways - MDSpire

Case Report: HIT-related valve thrombosis in an LVAD patient

  • By

  • Dan Wang

  • Haibo Ren

  • Wenjun Zhou

  • June 11, 2026

  • 0 min

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  • 1

    A 61-year-old male developed thrombus formation after LVAD implantation and aortic valve replacement due to heparin-induced thrombocytopenia (HIT).

  • 2

    Emergency thrombectomy revealed a white thrombus on the aortic root, necessitating a switch from heparin to argatroban for anticoagulation management.

  • 3

    The patient's platelet count improved significantly after initiating argatroban, leading to stabilization of LVAD flow and resolution of clinical symptoms.

  • 4

    This case emphasizes the importance of recognizing HIT in LVAD patients experiencing unexplained thrombosis and thrombocytopenia.

  • 5

    Postoperative thrombus formation poses significant challenges in managing anticoagulation, particularly in patients with LVAD and bioprosthetic valves.

Original Source(s)

Case Report: HIT-related valve thrombosis in an LVAD patient

  • by Dan Wang, Haibo Ren, Wenjun Zhou

  • June 11, 2026

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