Cardiometabolic Biomarkers and Systemic Inflammation in US Adolescents and Young Adults With Latent Tuberculosis Infection: A Population-Based Cohort Study

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Latent tuberculosis infection (LTBI) in older adolescents and young adults is associated with higher inflammation levels compared to uninfected peers.
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No significant differences in cardiometabolic health indicators were found between young individuals with LTBI and those without.
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The study utilized data from the National Health and Nutrition Examination Survey (NHANES) for analysis of LTBI and cardiometabolic health.
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Chronic inflammation due to LTBI may not lead to immediate cardiometabolic derangement in young people, unlike in adults.
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Further research is needed to explore the long-term consequences of chronic inflammation from LTBI on cardiometabolic health in youth.

Open Forum Infectious Diseases

by Itai M Magodoro, Ntobeko A B Ntusi, Jennifer Jao, Heather J Zar, Brian L Claggett, Mark J Siedner, Katalin A Wilkinson, Robert J Wilkinson
March 28, 2025

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