Blood Test Forecasts Alzheimer's Onset
Plasma p-tau217 “clocks” estimate timing of symptoms years before clinical diagnosis
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A blood test measuring phosphorylated tau217 can predict the onset of symptomatic Alzheimer's disease years in advance.
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Researchers developed statistical models using plasma p-tau217 levels to estimate the timing of cognitive symptom onset.
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The study indicates that p-tau217 levels rise progressively during the preclinical phase of Alzheimer's.
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P-tau217 clocks demonstrated predictive performance across diverse populations and correlated with established Alzheimer's markers.
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The blood test offers a cheaper and more accessible alternative to PET scans and spinal fluid tests for Alzheimer's prediction.
