Common Cold Coronavirus Test Positivity Decreased After Widespread SARS-CoV-2 Experience - Takeaways - MDSpire

Common Cold Coronavirus Test Positivity Decreased After Widespread SARS-CoV-2 Experience

  • By

  • Trisha Parayil

  • Janet Monroe

  • David J Bean

  • Manish Sagar

  • June 18, 2025

  • 0 min

Share

  • 1

    Test positivity for common cold coronaviruses significantly decreased after widespread SARS-CoV-2 infections and COVID-19 vaccinations.

  • 2

    There was approximately a 60% reduction in the odds of detecting common cold coronaviruses post-SARS-CoV-2 immunity.

  • 3

    No significant changes were observed in the test positivity rates for respiratory syncytial virus or influenza virus during the same period.

  • 4

    The study analyzed data from Boston Medical Center over multiple respiratory seasons before and after the COVID-19 pandemic.

  • 5

    Potential mechanisms for decreased ccCoV positivity include cross-reactive immunity and changes in healthcare practices.

Original Source(s)

Common Cold Coronavirus Test Positivity Decreased After Widespread SARS-CoV-2 Experience

  • by Trisha Parayil, Janet Monroe, David J Bean, Manish Sagar

  • June 18, 2025

Related Content

Serum cytokine profiling reveals CXCL10 (IP-10) as a major predictor of severe COVID-19 outcomes in hospitalized patients during the first pandemic wave in Italy

Early-Phase Oral Antiviral Use and Post–COVID-19 Condition in Outpatients

Case Report: Successful treatment of recurrent COVID-19 with intravenous immunoglobulin in a patient with rituximab-induced B-cell depletion and restoration of Fc-mediated effector functions