Case report: The masquerading spectrum: a pediatric case series of IgG4-related disease - Takeaways - MDSpire

Case report: The masquerading spectrum: a pediatric case series of IgG4-related disease

  • By

  • Olga Viktorovna Shpitonkova

  • Natalia Anatolievna Geppe

  • Vera Alekseevna Podzolkova

  • Elena Yurievna Afonina

  • Tatiana Vladimirovna Zubareva

  • Maria Nikolaevna Nikolaeva

  • Natalia Yurievna Golovanova

  • Maria Kirillovna Osminina

  • Elena Vasilievna Frolkova

  • Maria Alekseevna Kudryashova

  • Nadezhda Stepanovna Podchernyaeva

  • May 8, 2026

  • 0 min

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  • 1

    IgG4-related disease (IgG4-RD) is a rare fibro-inflammatory condition with limited data on its pediatric presentation and management.

  • 2

    The study analyzed six children with confirmed IgG4-RD, highlighting diverse clinical manifestations and diagnostic challenges.

  • 3

    Orbital involvement was the most common presentation, with patients experiencing symptoms like eyelid swelling and proptosis.

  • 4

    Treatment regimens varied, including glucocorticoids and cytostatic agents, with some patients achieving good clinical responses.

  • 5

    This case series emphasizes the need for increased awareness and understanding of pediatric IgG4-RD to improve diagnosis and management.

Original Source(s)

Case report: The masquerading spectrum: a pediatric case series of IgG4-related disease

  • by Olga Viktorovna Shpitonkova, Natalia Anatolievna Geppe, Vera Alekseevna Podzolkova, Elena Yurievna Afonina, Tatiana Vladimirovna Zubareva, Maria Nikolaevna Nikolaeva, Natalia Yurievna Golovanova, Maria Kirillovna Osminina, Elena Vasilievna Frolkova, Maria Alekseevna Kudryashova, Nadezhda Stepanovna Podchernyaeva

  • May 8, 2026

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