Impact of thrombosis on disease progression, cancer and mortality in patients with essential thrombocythemia and polycythemia vera - Takeaways - MDSpire
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The Role of Thrombotic Events in Disease Advancement, Cancer Incidence, and Mortality Among Patients with Essential Thrombocythemia and Polycythemia Vera

  • By

  • A. Angona

  • B. Cuevas

  • M. Pérez-Encinas

  • F. Ferrer-Marin

  • A. Senín

  • E. Arellano-Rodrigo

  • J. C. Hernández-Boluda

  • M. I. Mata Vázquez

  • G. Caballero-Navarro

  • M. T. Gómez-Casares

  • E. Magro

  • G. Carreño-Tarragona

  • M. A. Cortés-Vázquez

  • R. Pérez López

  • V. García-Gutiérrez

  • M. S. Noya-Pereira

  • J. M. Alonso-Dominguez

  • C. Sierra- Aisa

  • L. Fox

  • C. García Hernández

  • J. M. Guerra

  • E. Cerezo

  • M. Gasior

  • M. Santaliestra

  • I. Díez

  • M. V. Cuevas

  • L. Sanz

  • I. Pastor

  • R. Stuckey

  • P. Vélez

  • C. Auría-Caballero

  • A. Alvarez-Larrán

  • May 7, 2026

Share

  • 1

    Thrombotic events in patients with essential thrombocythemia (ET) and polycythemia vera (PV) significantly impact survival rates.

  • 2

    Arterial thrombosis (AT) is associated with a lower survival rate in both ET and PV patients compared to those without thrombosis.

  • 3

    The occurrence of second cancers (SC) was not significantly linked to thrombotic events in ET or PV patients.

  • 4

    JAK2V617F mutation status is a significant factor influencing the risk of death and second cancers in MPN patients.

  • 5

    Preventing arterial thrombosis is crucial in managing myeloproliferative neoplasms due to its association with worse prognostic outcomes.

Original Source(s)

Impact of thrombosis on disease progression, cancer and mortality in patients with essential thrombocythemia and polycythemia vera

  • by A. Angona, B. Cuevas, M. Pérez-Encinas, F. Ferrer-Marin, A. Senín, E. Arellano-Rodrigo, J. C. Hernández-Boluda, M. I. Mata Vázquez, G. Caballero-Navarro, M. T. Gómez-Casares, E. Magro, G. Carreño-Tarragona, M. A. Cortés-Vázquez, R. Pérez López, V. García-Gutiérrez, M. S. Noya-Pereira, J. M. Alonso-Dominguez, C. Sierra- Aisa, L. Fox, C. García Hernández, J. M. Guerra, E. Cerezo, M. Gasior, M. Santaliestra, I. Díez, M. V. Cuevas, L. Sanz, I. Pastor, R. Stuckey, P. Vélez, C. Auría-Caballero, A. Alvarez-Larrán

  • May 7, 2026

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