Impact of thrombosis on disease progression, cancer and mortality in patients with essential thrombocythemia and polycythemia vera

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Thrombotic events in patients with essential thrombocythemia (ET) and polycythemia vera (PV) significantly impact survival rates.
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Arterial thrombosis (AT) is associated with a lower survival rate in both ET and PV patients compared to those without thrombosis.
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The occurrence of second cancers (SC) was not significantly linked to thrombotic events in ET or PV patients.
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JAK2V617F mutation status is a significant factor influencing the risk of death and second cancers in MPN patients.
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Preventing arterial thrombosis is crucial in managing myeloproliferative neoplasms due to its association with worse prognostic outcomes.

Blood Cancer Journal

by A. Angona, B. Cuevas, M. Pérez-Encinas, F. Ferrer-Marin, A. Senín, E. Arellano-Rodrigo, J. C. Hernández-Boluda, M. I. Mata Vázquez, G. Caballero-Navarro, M. T. Gómez-Casares, E. Magro, G. Carreño-Tarragona, M. A. Cortés-Vázquez, R. Pérez López, V. García-Gutiérrez, M. S. Noya-Pereira, J. M. Alonso-Dominguez, C. Sierra- Aisa, L. Fox, C. García Hernández, J. M. Guerra, E. Cerezo, M. Gasior, M. Santaliestra, I. Díez, M. V. Cuevas, L. Sanz, I. Pastor, R. Stuckey, P. Vélez, C. Auría-Caballero, A. Alvarez-Larrán
May 7, 2026

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