Demographics and Geographic Accessibility of Invasive Fungal Infection Clinical Trial Sites - Takeaways - MDSpire

Demographics and Geographic Accessibility of Invasive Fungal Infection Clinical Trial Sites

  • By

  • Lucy X. Li

  • Jiashu Xue

  • Olivia S. Kates

  • Robin K. Avery

  • Sean X. Zhang

  • John W. Baddley

  • Christine M. Durand

  • Nitipong Permpalung

  • June 11, 2026

  • 0 min

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  • 1

    Clinical trials for invasive fungal infections (IFIs) are unevenly distributed, with a concentration in urban areas and significant regional variation.

  • 2

    Socioeconomically disadvantaged and rural populations face barriers to accessing clinical trials, potentially leading to disparities in trial representation.

  • 3

    A majority of residents near trial sites are of working age, with racial minorities more represented in prophylaxis trial catchments compared to treatment sites.

  • 4

    Many residents in trial catchment areas lack vehicle access, which may hinder participation in clinical trials despite proximity to sites.

  • 5

    The study underscores the need for equitable trial access strategies to capture diverse epidemiological data and improve antifungal drug development.

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