Diabetes Remission After LRYGBP With and Without Fundus Resection: a Randomized Clinical Trial - Takeaways - MDSpire

Diabetes Remission After LRYGBP With and Without Fundus Resection: a Randomized Clinical Trial

  • By

  • Dimitrios Kehagias

  • Charalampos Lampropoulos

  • Neoklis Georgopoulos

  • Ioannis Habeos

  • Dimitra Kalavrizioti

  • Sotirios-Spyridon Vamvakas

  • Panagiota Davoulou

  • Ioannis Kehagias

  • October 2, 2023

  • 0 min

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  • 1

    LRYGBP is an effective bariatric procedure that balances complication rates and metabolic benefits for patients with obesity and T2DM.

  • 2

    GLP-1 is a key gut hormone that enhances pancreatic b-cell response and insulin secretion, contributing significantly to T2DM remission.

  • 3

    Gastric fundus resection during LRYGBP may optimize antidiabetic effects by reducing ghrelin levels, potentially improving glycemic control.

  • 4

    The study included 24 patients with severe obesity and T2DM, assessing outcomes like HbA1c, BMI, and GI hormone levels over one year.

  • 5

    The trial adhered to ethical standards and was registered, highlighting the importance of rigorous methodology in clinical research.

Original Source(s)

Diabetes Remission After LRYGBP With and Without Fundus Resection: a Randomized Clinical Trial

  • by Dimitrios Kehagias, Charalampos Lampropoulos, Neoklis Georgopoulos, Ioannis Habeos, Dimitra Kalavrizioti, Sotirios-Spyridon Vamvakas, Panagiota Davoulou, Ioannis Kehagias

  • October 2, 2023

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