Diagnosis and treatment strategies for airway involvement in relapsing polychondritis: a comprehensive review - Takeaways - MDSpire

Diagnosis and treatment strategies for airway involvement in relapsing polychondritis: a comprehensive review

  • By

  • Pengcheng Zhou

  • Wei Yu

  • Jianli Ma

  • Wensheng Zhang

  • Yan Dong

  • Chengshi He

  • June 4, 2026

  • 0 min

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  • 1

    Relapsing polychondritis (RP) is a rare autoimmune disease that primarily affects cartilage, leading to severe airway complications.

  • 2

    Airway involvement occurs in approximately 50% of RP patients and significantly impacts prognosis and survival rates.

  • 3

    Diagnosis of airway lesions in RP is challenging due to nonspecific symptoms and the lack of specific laboratory indicators.

  • 4

    Traditional treatments include glucocorticoids and immunosuppressants, but some patients may require bronchial interventions for severe airway stenosis.

  • 5

    Emerging therapies, such as biologics and ECMO-supported interventions, offer new options for managing severe airway complications in RP.

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