Effects of low anterior resection syndrome after colorectal cancer resections on health-related quality of life: a systematic review and meta-analysis - Takeaways - MDSpire

Effects of low anterior resection syndrome after colorectal cancer resections on health-related quality of life: a systematic review and meta-analysis

  • By

  • S. Shojaei-Zarghani

  • K. Gorgi

  • A. Bananzadeh

  • A. R. Safarpour

  • S. V. Hosseini

  • May 10, 2025

  • 0 min

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  • 1

    Colorectal cancer is the second most prevalent cancer and a leading cause of cancer-related mortality globally.

  • 2

    Low anterior resection syndrome (LARS) significantly affects bowel function and health-related quality of life in rectal cancer patients.

  • 3

    The incidence of LARS one year post-surgery is high, reported at 44%, with major risk factors including female sex and anastomotic leakage.

  • 4

    This systematic review aims to assess the impact of LARS on health-related quality of life using the LARS score and EORTC QLQ-C30.

  • 5

    Understanding LARS's effects on quality of life is essential for effective preoperative counseling and patient care.

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