Childhood-onset inflammatory bowel disease and chronic non-bacterial osteomyelitis: a Swedish nationwide cohort study 2002-2022 - Takeaways - MDSpire

Childhood-onset inflammatory bowel disease and chronic non-bacterial osteomyelitis: a Swedish nationwide cohort study 2002-2022

  • By

  • Marianne Malmquist

  • Siri Voghera

  • The SWIBREG Study Group

  • Stefan Berg

  • Robert Saalman

  • Ola Olén

  • January 13, 2025

  • 0 min

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  • 1

    A nationwide study in Sweden identified 8244 children with childhood-onset inflammatory bowel disease (IBD) from 2002 to 2022.

  • 2

    The study found a 6-fold increased risk of chronic non-bacterial osteomyelitis (CNO) in children with IBD compared to non-IBD peers.

  • 3

    At IBD diagnosis, CNO was present in 0.13% of the IBD cohort and 0.03% of non-IBD comparators, indicating a significant association.

  • 4

    Patients with IBD and CNO had a lower median age at IBD diagnosis and more frequent extraintestinal manifestations than those without CNO.

  • 5

    Biologic treatment was more common in the IBD+CNO group, with 78% receiving biologics compared to 44% in the IBD-only group.

Original Source(s)

Childhood-onset inflammatory bowel disease and chronic non-bacterial osteomyelitis: a Swedish nationwide cohort study 2002-2022

  • by Marianne Malmquist, Siri Voghera, The SWIBREG Study Group, Stefan Berg, Robert Saalman, Ola Olén

  • January 13, 2025

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