Pediatric Antibiotic Use Associated With Respiratory Syncytial Virus and Influenza in the United States, 2008–2018 - Takeaways - MDSpire
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Association of Pediatric Antibiotic Prescriptions with Respiratory Syncytial Virus and Influenza in the United States from 2008 to 2018

  • By

  • Laura M King

  • Katia J Bruxvoort

  • Sara Y Tartof

  • Joseph A Lewnard

  • June 7, 2025

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  • 1

    6.3% of pediatric antibiotic prescriptions were associated with respiratory syncytial virus (RSV) and 3.4% with influenza from 2008 to 2018.

  • 2

    The highest incidence of RSV-associated antibiotic prescriptions occurred in children aged 5 years or younger, while influenza-associated prescriptions peaked in older children.

  • 3

    Macrolides were the antibiotic class most influenced by RSV and influenza, indicating a significant impact on prescribing practices.

  • 4

    Preventive measures, including immunization against RSV and influenza, may help reduce antibiotic use and combat antibiotic resistance in children.

  • 5

    The study utilized time series models to analyze antibiotic prescription rates in relation to RSV and influenza circulation patterns.

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