Asymmetric efficacy of VNS within a single patient with bilateral focal frontal lobe epilepsy: A case report - Takeaways - MDSpire

Asymmetric efficacy of VNS within a single patient with bilateral focal frontal lobe epilepsy: A case report

  • By

  • Masanobu Kumon

  • Shunsuke Nakae

  • Daijiro Kojima

  • Noeru Kawase

  • Yuichi Hirose

  • August 26, 2025

  • 0 min

Share

  • 1

    Vagus nerve stimulation (VNS) is a surgical option for drug-resistant epilepsy, modulating thalamic and limbic networks.

  • 2

    This case report details a patient with bilateral frontal lobe epilepsy who experienced reduced seizures after VNS therapy.

  • 3

    Postoperative stereoelectroencephalography (SEEG) showed a significant decrease in seizures from the right hemisphere.

  • 4

    The patient underwent VNS after inadequate seizure control with multiple antiseizure medications and prior tumor resections.

  • 5

    This study highlights the importance of seizure lateralization in VNS efficacy, providing new insights into treatment planning.

Original Source(s)

Asymmetric efficacy of VNS within a single patient with bilateral focal frontal lobe epilepsy: A case report

  • by Masanobu Kumon, Shunsuke Nakae, Daijiro Kojima, Noeru Kawase, Yuichi Hirose

  • August 26, 2025

Related Content

Correction to: Threshold of somatic mosaicism leading to brain dysfunction with focal epilepsy

  • February 11, 2025

MRI-guided laser interstitial thermal therapy in epilepsy: indications, technique and outcome in an adult population. A single-center data analysis

Pediatricians at the Perioperative Helm

Pediatricians “uniquely positioned” to take active role in preanesthesia planning, says revised American Academy of Pediatrics report