Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure – the prenatal and postnatal echocardiographic course - Takeaways - MDSpire

Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure – the prenatal and postnatal echocardiographic course

  • By

  • Xiaohong Zhang

  • Guozhen Yuan

  • Kunpeng Li

  • Yangcan Duan

  • Junli Hu

  • Dongchen Fan

  • May 22, 2026

  • 0 min

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  • 1

    Persistent fifth aortic arch with fourth aortic arch interruption is a rare congenital malformation often misdiagnosed during prenatal ultrasound.

  • 2

    The male infant presented with worsening cough at 90 days of life, leading to a diagnosis of PFAA with coarctation and fourth arch interruption.

  • 3

    Surgical intervention included resection of the coarctation and reconstruction of the aortic arch, resulting in improved left ventricular function.

  • 4

    Prenatal detection of PFAA is extremely low due to subtle hemodynamic changes, highlighting the need for increased awareness among sonographers.

  • 5

    This case emphasizes the importance of understanding prenatal features and postnatal management for better outcomes in rare aortic arch anomalies.

Original Source(s)

Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure – the prenatal and postnatal echocardiographic course

  • by Xiaohong Zhang, Guozhen Yuan, Kunpeng Li, Yangcan Duan, Junli Hu, Dongchen Fan

  • May 22, 2026

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