The correlation between fine needle aspiration diagnosis and postoperative histopathological results of pediatric thyroid nodules based on the Bethesda system - Takeaways - MDSpire

The correlation between fine needle aspiration diagnosis and postoperative histopathological results of pediatric thyroid nodules based on the Bethesda system

  • By

  • Xue Bai

  • Jingjing Xu

  • Na Wei

  • Lin Xiao

  • Jinjuan Chen

  • June 1, 2026

  • 0 min

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  • 1

    Pediatric thyroid nodules have higher malignancy rates than adult nodules, necessitating accurate diagnostic evaluation.

  • 2

    The study analyzed 696 pediatric patients who underwent FNA for thyroid nodules, correlating results with histopathological findings.

  • 3

    The overall risk of malignancy ranged from 32.76% to 92.68%, increasing progressively across Bethesda categories.

  • 4

    Papillary thyroid carcinoma was the most common diagnosis, found in 88.62% of malignant cases, with BRAF V600E mutations in 51.53%.

  • 5

    The Bethesda system demonstrated high diagnostic accuracy, with sensitivity of 98.58% and specificity of 100% for definitive cytological categories.

Original Source(s)

The correlation between fine needle aspiration diagnosis and postoperative histopathological results of pediatric thyroid nodules based on the Bethesda system

  • by Xue Bai, Jingjing Xu, Na Wei, Lin Xiao, Jinjuan Chen

  • June 1, 2026

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