Exposure to aircraft noise exacerbates cardiovascular and oxidative damage in three mouse models of diabetes - Takeaways - MDSpire

Exposure to aircraft noise exacerbates cardiovascular and oxidative damage in three mouse models of diabetes

  • By

  • Dominika Mihalikova

  • Paul Stamm

  • Miroslava Kvandova

  • Chinmayi Pednekar

  • Lea Strohm

  • Henning Ubbens

  • Matthias Oelze

  • Marin Kuntic

  • Claudius Witzler

  • Maria Teresa Bayo Jimenez

  • Sanela Rajlic

  • Katie Frenis

  • Qi Tang

  • Yue Ruan

  • Susanne Karbach

  • Hartmut Kleinert

  • Omar Hahad

  • Alex von Kriegsheim

  • Ning Xia

  • Tilman Grune

  • Huige Li

  • Swenja Kröller-Schön

  • Adrian Gericke

  • Wolfram Ruf

  • Philipp S Wild

  • Philipp Lurz

  • Thomas Münzel

  • Andreas Daiber

  • Thomas Jansen

  • October 1, 2024

  • 0 min

Share

  • 1

    Aircraft noise exposure exacerbates cardiovascular and oxidative stress in diabetic mice models, indicating a potential risk for diabetic patients.

  • 2

    Noise exposure reduced insulin production and increased blood pressure in all diabetes models, highlighting its detrimental effects on metabolic function.

  • 3

    In the high-fat diet model, noise exposure led to additive aggravation of glucose tolerance and increased inflammation in adipose tissue.

  • 4

    Gene analyses revealed combined effects of noise and diabetes on inflammation and metabolism, suggesting shared signaling pathways.

  • 5

    The study underscores the need for further research on the impact of noise on cardiovascular risk in vulnerable populations, particularly those with diabetes.

Original Source(s)

Exposure to aircraft noise exacerbates cardiovascular and oxidative damage in three mouse models of diabetes

  • by Dominika Mihalikova, Paul Stamm, Miroslava Kvandova, Chinmayi Pednekar, Lea Strohm, Henning Ubbens, Matthias Oelze, Marin Kuntic, Claudius Witzler, Maria Teresa Bayo Jimenez, Sanela Rajlic, Katie Frenis, Qi Tang, Yue Ruan, Susanne Karbach, Hartmut Kleinert, Omar Hahad, Alex von Kriegsheim, Ning Xia, Tilman Grune, Huige Li, Swenja Kröller-Schön, Adrian Gericke, Wolfram Ruf, Philipp S Wild, Philipp Lurz, Thomas Münzel, Andreas Daiber, Thomas Jansen

  • October 1, 2024

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