SARS-CoV-2 During Pregnancy—Emerging Evidence of Uncommon Complications

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Maternal SARS-CoV-2 infection poses significant risks, including severe COVID-19 and potential adverse perinatal outcomes.
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A study found a slight increase in congenital anomalies among infants born to mothers with SARS-CoV-2 infection, but results were not statistically significant.
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The study's limitations include potential misclassification of asymptomatic infections and exclusion of stillbirths from the analysis.
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Despite the lack of definitive evidence, there are biological plausibility and prior studies suggesting a potential link between SARS-CoV-2 and congenital anomalies.
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The findings support the recommendation for COVID-19 vaccination in pregnant individuals due to maternal risks and the vaccine's safety profile.

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