Impact of Non-Invasive Brain Stimulation on Spontaneous Neural Activity in Patients with Post-Stroke Aphasia: A Protocol for a Coordinate-Based Meta-Analysis of fALFF Research - Takeaways - MDSpire

Impact of Non-Invasive Brain Stimulation on Spontaneous Neural Activity in Patients with Post-Stroke Aphasia: A Protocol for a Coordinate-Based Meta-Analysis of fALFF Research

  • By

  • Yao Rao

  • Jingjing Zhang

  • Jiawei Ni

  • Ming Zeng

  • Jiali Wu

  • Hui Xu

  • Zhiwei Zhao

  • Cong Wang

  • Chunlei Shan

  • April 22, 2026

  • 0 min

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  • 1

    Post-stroke aphasia (PSA) significantly impairs quality of life and affects approximately one-third of stroke survivors.

  • 2

    Non-invasive brain stimulation (NIBS) techniques like rTMS and tDCS are emerging as adjunctive therapies for language recovery in PSA.

  • 3

    This protocol outlines a coordinate-based meta-analysis to investigate how NIBS affects intrinsic neural activity in PSA patients.

  • 4

    The study will synthesize resting-state fMRI data to clarify the neural mechanisms underlying NIBS-induced improvements in PSA.

  • 5

    Findings from this meta-analysis aim to enhance understanding of NIBS effects and inform future rehabilitation strategies for PSA.

Original Source(s)

Impact of Non-Invasive Brain Stimulation on Spontaneous Neural Activity in Patients with Post-Stroke Aphasia: A Protocol for a Coordinate-Based Meta-Analysis of fALFF Research

  • by Yao Rao, Jingjing Zhang, Jiawei Ni, Ming Zeng, Jiali Wu, Hui Xu, Zhiwei Zhao, Cong Wang, Chunlei Shan

  • April 22, 2026

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