Treating without guidelines: management and outcomes of lung cancer diagnosed during pregnancy — a systematic review - Takeaways - MDSpire

Treating without guidelines: management and outcomes of lung cancer diagnosed during pregnancy — a systematic review

  • By

  • Nehemias Guevara Rodriguez

  • Noemy Coreas

  • Coral Olazagasti

  • Martina Imbimbo

  • Narjust Florez

  • May 13, 2026

  • 0 min

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  • 1

    Lung cancer diagnosed during pregnancy is rare, with most cases presenting at advanced stages, particularly stage III–IV.

  • 2

    Tobacco use is associated with advanced lung cancer stages in pregnant patients, reported in 33% of cases.

  • 3

    Chemotherapy during pregnancy is administered in 22.8% of cases, primarily during the second and third trimesters.

  • 4

    Among reported pregnancies, 71.9% resulted in live births, with advanced disease linked to adverse fetal outcomes.

  • 5

    Multidisciplinary management and routine molecular profiling are crucial for optimizing treatment and improving outcomes.

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