Dose–response relationship of exercise interventions on sleep quality in patients with depression: a systematic review and meta-analysis - Takeaways - MDSpire

Dose–response relationship of exercise interventions on sleep quality in patients with depression: a systematic review and meta-analysis

  • By

  • Ziqi Gao

  • Sujie Mao

  • Yaxin Wang

  • Huimin Yang

  • Chang Liu

  • Jiahe Wu

  • Jianxin Kang

  • June 30, 2026

  • 0 min

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  • 1

    This meta-analysis evaluated the effects of exercise interventions on sleep quality in patients with depression.

  • 2

    Seventeen publications involving 1,457 participants were included, showing significant improvements in sleep quality.

  • 3

    Exercise doses around 312.75 MET·min/week were associated with greater improvements in sleep quality.

  • 4

    Subgroup analyses indicated that mind-body exercises and specific durations and frequencies of exercise were beneficial.

  • 5

    The study suggests a need for larger multicenter RCTs to confirm the dose-response patterns and subgroup findings.

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