Molecular testing, first-line treatment patterns, and survival in metastatic Colombian non–small cell lung cancer: the RECAPC multicenter registry - Takeaways - MDSpire

Molecular testing, first-line treatment patterns, and survival in metastatic Colombian non–small cell lung cancer: the RECAPC multicenter registry

  • By

  • Ricardo Brugés

  • Pedro Ramos

  • Milton Lombana

  • Anderson Osma

  • Néstor Llinás

  • Javier Cuello

  • Andrés Yepes

  • Ray Manneh

  • Anabelly Coronel

  • Rebeca Granadillo

  • Carolina López

  • Álvaro Osorio

  • Daniel Santa

  • Natalia Arango

  • William Mantilla

  • Diego Gómez

  • July 17, 2026

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  • 1

    The RECAPC registry included 585 patients with metastatic non-small cell lung cancer, with a mean age of 72 years and 52% female.

  • 2

    Molecular profiling revealed 32.8% of patients had EGFR/ALK alterations, while 47.5% were not tested or had unknown driver status.

  • 3

    First-line treatment patterns included chemotherapy alone (34.4%), targeted therapy (26.7%), and chemo-immunotherapy (21.0%).

  • 4

    Overall survival analysis showed significant differences by driver group, with not tested/unknown status associated with higher mortality.

  • 5

    Incomplete molecular characterization and missing treatment documentation were common, reflecting systemic barriers in Colombian healthcare.

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