Organ Damage, BMI Linked to Fatigue in SLE
Cross-sectional study suggests fatigue is associated with damage accrual and body mass, not disease activity
-
By
-
Andrea Surnit
-
April 20, 2026
-
-
1
Clinically significant fatigue in systemic lupus erythematosus is linked to greater organ damage and higher body mass index.
-
2
The study involved 183 patients, with 52% reporting clinically significant fatigue measured by the Fatigue Severity Scale.
-
3
Fatigue was not associated with disease activity, as patients had low mean SELENA-SLEDAI scores.
-
4
Racial differences were noted, with non-Hispanic White patients more likely to report significant fatigue than Black patients.
-
5
Pulmonary fibrosis and neuropathy were independently associated with fatigue severity, highlighting the need for further research.
