Active Surveillance of Highly Suspicious Thyroid Nodules in the Isthmus Compared with Non-Isthmus Locations: A Multicenter Retrospective Study - Takeaways - MDSpire

Active Surveillance of Highly Suspicious Thyroid Nodules in the Isthmus Compared with Non-Isthmus Locations: A Multicenter Retrospective Study

  • By

  • Hu, Yan

  • Zhou, Wei

  • Li, Cheng

  • Zhang, Lu

  • Zhan, Weiwei

  • April 22, 2026

  • 0 min

Share

  • 1

    The study compared progression outcomes of highly suspicious thyroid nodules in the isthmus versus non-isthmic regions.

  • 2

    A total of 449 solitary thyroid nodules were analyzed, with 33 located in the isthmus and 416 in non-isthmic areas.

  • 3

    No significant differences in progression rates were found between isthmic and non-isthmic nodules during active surveillance.

  • 4

    The study observed a composite endpoint occurrence of 3.03% in the isthmus group and 4.09% in the non-isthmus group.

  • 5

    Findings suggest that active surveillance may be feasible for selected isthmic thyroid nodules, despite the small sample size.

Original Source(s)

Active Surveillance of Highly Suspicious Thyroid Nodules in the Isthmus Compared with Non-Isthmus Locations: A Multicenter Retrospective Study

  • by Hu, Yan , Zhou, Wei , Li, Cheng , Zhang, Lu , Zhan, Weiwei

  • April 22, 2026

Related Content

Case Report: First description of an intracranial “NET” in ROHHAD syndrome; time to rename to the ROHHAD-NeCT syndrome?

Increasing incidence and severity of childhood-onset type 1 diabetes in Latvia during the COVID-19 pandemic

3 Medical Routines That Older People May Not Need

“The treatment may be more burdensome than the condition itself."