Reply to the Letter to the Editor: Radiation exposure and screening yield by digital breast tomosynthesis compared to mammography—results of the TOSYMA trial breast density related - Takeaways - MDSpire

Reply to the Letter to the Editor: Radiation exposure and screening yield by digital breast tomosynthesis compared to mammography—results of the TOSYMA trial breast density related

  • By

  • Alexander Sommer

  • Stefanie Weigel

  • Hans-Werner Hense

  • Elke Nekolla

  • Veronika Weyer-Elberich

  • Walter Heindel

  • August 19, 2025

  • 0 min

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  • 1

    The TOSYMA trial evaluates radiation exposure and screening yield of digital breast tomosynthesis compared to digital mammography.

  • 2

    The study acknowledges higher breast doses with DBT + SM but suggests improved cancer detection may favor its use for women with dense breasts.

  • 3

    Cost-effectiveness analyses are needed to assess the public health implications of TOSYMA's findings and the impact of technological innovations.

  • 4

    TOSYMA is a pragmatic RCT using various mammography devices, enhancing the generalizability of its findings in population screening.

  • 5

    The trial emphasizes the importance of innovative technologies and risk-adapted screening strategies in future breast cancer research.

Original Source(s)

Reply to the Letter to the Editor: Radiation exposure and screening yield by digital breast tomosynthesis compared to mammography—results of the TOSYMA trial breast density related

  • by Alexander Sommer, Stefanie Weigel, Hans-Werner Hense, Elke Nekolla, Veronika Weyer-Elberich, Walter Heindel

  • August 19, 2025

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