Changes in serial multiparametric MRI and FDG-PET/CT functional imaging during radiation therapy can predict treatment response in patients with head and neck cancer - Takeaways - MDSpire
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Predictive Value of Serial Multiparametric MRI and FDG-PET/CT Imaging Changes During Radiation Therapy for Treatment Outcomes in Head and Neck Cancer Patients

  • By

  • Yuvnik Trada

  • Paul Keall

  • Michael Jameson

  • Daniel Moses

  • Peter Lin

  • Phillip Chlap

  • Lois Holloway

  • Myo Min

  • Dion Forstner

  • Allan Fowler

  • Mark T. Lee

  • July 5, 2023

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  • 1

    Definitive radiotherapy is a standard treatment for locally advanced head and neck squamous cell carcinoma, but recurrence remains a significant issue.

  • 2

    Functional imaging, particularly DWI and FDG-PET/CT, can non-invasively monitor tumor changes during treatment and may serve as early biomarkers for response.

  • 3

    Changes in functional imaging during treatment are more predictive of treatment response than pre-treatment imaging, highlighting the need for mid-treatment assessments.

  • 4

    The study aims to evaluate the predictive value of serial multiparametric MRI and FDG-PET/CT in assessing treatment response in head and neck cancer.

  • 5

    Optimal timing for mid-treatment imaging remains unclear, necessitating further research to refine imaging protocols for better treatment adaptation.

Original Source(s)

Changes in serial multiparametric MRI and FDG-PET/CT functional imaging during radiation therapy can predict treatment response in patients with head and neck cancer

  • by Yuvnik Trada, Paul Keall, Michael Jameson, Daniel Moses, Peter Lin, Phillip Chlap, Lois Holloway, Myo Min, Dion Forstner, Allan Fowler, Mark T. Lee

  • July 5, 2023

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