Sleep-related problems among patients with rheumatoid arthritis in the World Health Organization Eastern Mediterranean region: a systematic review and meta-analysis - Takeaways - MDSpire

Sleep-related problems among patients with rheumatoid arthritis in the World Health Organization Eastern Mediterranean region: a systematic review and meta-analysis

  • By

  • Mohammad Mustafa

  • May 29, 2026

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  • 1

    The pooled prevalence of sleep-related problems among rheumatoid arthritis patients in WHO EMRO countries is 60.9%.

  • 2

    Insomnia symptoms, obstructive sleep apnea, and poor subjective sleep quality have prevalence estimates of 58%, 65%, and 61%, respectively.

  • 3

    Depression is the strongest associated factor for sleep-related problems in rheumatoid arthritis patients, with an odds ratio of 2.65.

  • 4

    Other significant correlates of sleep-related issues include pain, fatigue, female gender, and older age.

  • 5

    The study highlights the need for standardized diagnostic criteria and larger longitudinal studies to better understand sleep disorders in this population.

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