Acute liver failure and secondary TMA-like phenomenon following SARS-CoV-2 and Mycoplasma pneumoniae co-detection in a child: a case report - Takeaways - MDSpire

Acute liver failure and secondary TMA-like phenomenon following SARS-CoV-2 and Mycoplasma pneumoniae co-detection in a child: a case report

  • By

  • Qian Liu

  • Ting Kang

  • Wenjuan Zeng

  • Yuan Long

  • May 28, 2026

  • 0 min

Share

  • 1

    A 20-month-old girl with concurrent SARS-CoV-2 and Mycoplasma pneumoniae infections presented with sepsis and acute liver failure.

  • 2

    Initial lab results showed extreme hyperinflammation, with ALT at 17,134 U/L and ferritin at 10,929.6 ng/mL.

  • 3

    The patient developed a secondary thrombotic microangiopathy-like phenomenon characterized by severe thrombocytopenia and acute kidney injury.

  • 4

    Negative complement gene testing supported a diagnosis of severe infection-associated secondary TMA-like phenomenon.

  • 5

    The patient recovered after comprehensive supportive care, antimicrobial therapy, glucocorticoids, and prophylactic anticoagulation.

Original Source(s)

Acute liver failure and secondary TMA-like phenomenon following SARS-CoV-2 and Mycoplasma pneumoniae co-detection in a child: a case report

  • by Qian Liu, Ting Kang, Wenjuan Zeng, Yuan Long

  • May 28, 2026

Related Content

Side Effects: Salt, Steroids, and Second Brains

So get this: sodium may track with memory decline (in men), steroids might not be “immunosuppressive” in the ICU, and second pregnancies reshape the brain differently than first. Same theme: biology is less binary than we teach it.

The Role of Neutrophil-to-Lymphocyte Ratio in Severe Neonatal SARS-CoV-2 Infections: Links to Changes in Lymphocyte Subpopulations

Research progress on risk factors and clinical management of Ureaplasma Species infection in preterm infants