Comprehensive Evaluation of miR-15a-5p, miR-20a-5p, and miR-33b-3p Reveals EGR2-Related Biomarkers in Multiple Myeloma - Takeaways - MDSpire

Comprehensive Evaluation of miR-15a-5p, miR-20a-5p, and miR-33b-3p Reveals EGR2-Related Biomarkers in Multiple Myeloma

  • By

  • Riham Abdel-Hamid Haroun

  • Nada M. Ismail

  • Samar S. Elshazly

  • Fatma F. Abdel Hamid

  • Reem Nabil

  • February 12, 2026

  • 0 min

Share

  • 1

    Multiple myeloma (MM) is a prevalent hematologic malignancy characterized by over 10% plasma cells in the bone marrow.

  • 2

    MicroRNAs, including miR-15a-5p, miR-20a-5p, and miR-33b-3p, play critical roles in the pathogenesis of multiple myeloma.

  • 3

    The study investigates the molecular roles of specific microRNAs and their relationship with EGR2 in MM pathogenesis.

  • 4

    Patients with newly diagnosed MM were included in the study, with strict inclusion and exclusion criteria applied.

  • 5

    Bioinformatics analysis was conducted to explore the target genes and biological processes associated with the studied microRNAs.

Original Source(s)

Comprehensive Evaluation of miR-15a-5p, miR-20a-5p, and miR-33b-3p Reveals EGR2-Related Biomarkers in Multiple Myeloma

  • by Riham Abdel-Hamid Haroun, Nada M. Ismail, Samar S. Elshazly, Fatma F. Abdel Hamid, Reem Nabil

  • February 12, 2026

Related Content

Optimisation of patient-reported outcome measurement for haematological cancer patients receiving novel immunotherapies: perspectives of multi-stakeholders

Unsupervised risk factor identification across cancer types and data modalities via explainable artificial intelligence

Biochemical Tumor Markers: Are New Testing Guidelines Fit for Purpose?

CLSI guidance achieves technical excellence but has some questionable omissions, says Mustafa Barbhuiya