Antibiotic prophylaxis in patients who had undergone to prostate biopsy in between the EMA warning era: effects of fluoroquinolones in diabetic and non-diabetic patients. Results of an observational cohort study - Takeaways - MDSpire

Antibiotic prophylaxis in patients who had undergone to prostate biopsy in between the EMA warning era: effects of fluoroquinolones in diabetic and non-diabetic patients. Results of an observational cohort study

  • By

  • Riccardo Bartoletti

  • Francesco Claps

  • Gabriele Tulone

  • Alessandro Perotti

  • Alessandro Zucchi

  • Niccolò Riccardi

  • Vincenzo Ficarra

  • Cosimo De Nunzio

  • Andrea Tubaro

  • Alchiede Simonato

  • June 10, 2022

  • 0 min

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  • 1

    Diabetic patients are at a higher risk for urinary tract infections (UTIs) following trans-rectal ultrasound-guided prostate biopsy (TRUSPB).

  • 2

    The incidence of UTIs after TRUSPB increased from 6.1% to 9.7% between 2010 and 2019, with serious complications including hospitalization and sepsis.

  • 3

    Current antibiotic prophylaxis recommendations for TRUSPB vary, with the European Association of Urology advising against fluoroquinolones due to safety concerns.

  • 4

    A multi-center cohort study analyzed 143 diabetic patients to evaluate the effectiveness of different antibiotic prophylaxis regimens during the EMA warning period.

  • 5

    The study aimed to assess the relationship between antibiotic prophylaxis types and the risk of infective complications in patients undergoing TRUSPB.

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