Subtypes of Symptoms and Endoscopic Findings in Gastro-oesophageal Reflux Disease: A Retrospective Cross-Sectional Analysis from Southwestern Nigeria

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Gastro-oesophageal reflux disease (GORD) has a global prevalence of 13.3%, with significant variations among countries.
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In Nigeria, non-erosive reflux disease (NERD) is the predominant form of GORD, affecting 74.5% of patients.
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The study analyzed 411 eligible patients with GORD symptoms and upper gastrointestinal endoscopy findings.
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Oesophageal symptoms include heartburn and regurgitation, while extra-oesophageal symptoms encompass a range of respiratory and digestive issues.
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Endoscopic findings in GORD can include mucosal injury, with the study aiming to correlate symptom subtypes with these findings.

Bmc Gastroenterology

by E Odeghe, A Itam-Eyo, A Oluyemi, O Owoseni, A Nnadi, J Uchechukwu, O Onodingene, S Tamunodukobipi, O Adeniyi, M Lawal, G Oyeleke
October 24, 2025

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