Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials - Takeaways - MDSpire

Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials

  • By

  • Yanhao Wang

  • Zhengnian Lin

  • Ji Zhu

  • Wei Gao

  • Zhiheng Li

  • Xiaoyan Li

  • Ming Li

  • June 24, 2026

  • 0 min

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  • 1

    This systematic review and meta-analysis examined the effects of resistance training on vascular function in adults with hypertension or obesity-related risk.

  • 2

    Twenty randomized controlled trials were included, showing resistance training significantly reduced arterial stiffness and improved flow-mediated dilation (FMD).

  • 3

    The reduction in arterial stiffness was quantified with a Hedge's g of -0.18, while FMD showed a significant improvement with a Hedge's g of 0.70.

  • 4

    Caution is advised in interpreting FMD results due to potential publication bias and the limited evidence base surrounding these findings.

  • 5

    No significant benefits were observed for wave reflection indices, and evidence for peripheral hemodynamic outcomes was deemed insufficient.

Original Source(s)

Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials

  • by Yanhao Wang, Zhengnian Lin, Ji Zhu, Wei Gao, Zhiheng Li, Xiaoyan Li, Ming Li

  • June 24, 2026

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