Evening Chronotype Linked to Cardiovascular Risk - Takeaways - MDSpire

Evening Chronotype Linked to Cardiovascular Risk

  • By

  • Kathryn Wighton

  • January 26, 2026

  • 3 min

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  • 1

    Evening chronotype is associated with a 16% higher risk of cardiovascular disease compared to intermediate chronotype.

  • 2

    Approximately 75% of the cardiovascular risk linked to evening chronotype is mediated by lower attainment of AHA's Life’s Essential 8 metrics.

  • 3

    Participants with a definite evening chronotype showed a 79% higher prevalence of unfavorable LE8 scores than those with an intermediate chronotype.

  • 4

    Poorer LE8 scores were observed across six components, with nicotine exposure and inadequate sleep being the strongest associations.

  • 5

    The study's limitations include potential misclassification of chronotype and a predominantly White, healthier participant cohort.

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