Pilot feasibility study of intraprocedural transcranial Doppler monitoring to assess Heal coating thrombogenicity in flow diversion - Takeaways - MDSpire

Pilot feasibility study of intraprocedural transcranial Doppler monitoring to assess Heal coating thrombogenicity in flow diversion

  • By

  • Anil Arat

  • Ezgi Yilmaz

  • Sinan Balci

  • Ferdi Cay

  • Charles Matouk

  • Mehmet Akif Topcuoğlu

  • June 24, 2026

  • 0 min

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  • 1

    The study utilized transcranial Doppler ultrasonography to assess thromboembolic events during flow diversion for cerebral aneurysms.

  • 2

    Thirteen patients were treated with the bare Derivo2 FD under dual antiplatelet therapy, while thirteen received the coated Derivo 2heal FD under single antiplatelet therapy.

  • 3

    The bare Derivo2 FD group exhibited a higher incidence of solid emboli within 30 minutes post-deployment compared to the coated version.

  • 4

    Exclusion of one patient from the coated group resulted in a marginal significance in emboli detection, indicating variability in results.

  • 5

    The study concluded that DWI findings are not reliable for determining the thrombogenicity of flow diverters, warranting further research.

Original Source(s)

Pilot feasibility study of intraprocedural transcranial Doppler monitoring to assess Heal coating thrombogenicity in flow diversion

  • by Anil Arat, Ezgi Yilmaz, Sinan Balci, Ferdi Cay, Charles Matouk, Mehmet Akif Topcuoğlu

  • June 24, 2026

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