Surgery confers survival benefit in De Novo metastatic soft tissue sarcoma patients with low Ki67 or low total lesion glycolysis: a combined PET/CT and clinicopathological analysis - Takeaways - MDSpire

Surgery confers survival benefit in De Novo metastatic soft tissue sarcoma patients with low Ki67 or low total lesion glycolysis: a combined PET/CT and clinicopathological analysis

  • By

  • Shaoli Li

  • Xin Zheng

  • Menglei Jin

  • Hui Wang

  • Rui Bai

  • Ying Dong

  • July 10, 2026

  • 0 min

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  • 1

    Soft tissue sarcomas account for less than 1% of adult cancers but contribute significantly to cancer-related morbidity and mortality.

  • 2

    The role of surgical intervention for primary tumors in de novo metastatic soft tissue sarcoma remains controversial and poorly defined.

  • 3

    This study evaluated the prognostic value of ¹⁸F-FDG PET/CT metabolic parameters in patients with de novo metastatic soft tissue sarcoma.

  • 4

    A total of 40 patients with de novo metastatic soft tissue sarcoma were included in the retrospective analysis of this study.

  • 5

    The study aimed to explore the interaction between PET/CT-derived metrics and the potential survival benefit of primary tumor surgery.

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