Diagnostic accuracy of blast-induced traumatic brain injury: a systematic review and meta-analysis - Takeaways - MDSpire

Diagnostic accuracy of blast-induced traumatic brain injury: a systematic review and meta-analysis

  • By

  • Peiqi Zhang

  • Lanxin Qin

  • Fulin Wang

  • Pengfei Wu

  • Liang Zhang

  • Danna Fang

  • Jingmei Zhao

  • Yuan Yao

  • Hui Zhao

  • July 13, 2026

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  • 1

    This systematic review evaluated diagnostic approaches for primary blast-induced traumatic brain injury (bTBI) through meta-analysis.

  • 2

    The meta-analysis revealed high diagnostic accuracy with pooled sensitivity of 0.93 and specificity of 0.90 across included studies.

  • 3

    Biomarker-based and neuroimaging approaches showed good diagnostic accuracy but are often inaccessible in acute battlefield scenarios.

  • 4

    The Vestibular/Ocular Motor Screening (VOMS) assessment may be more suitable for front-line use in diagnosing bTBI.

  • 5

    The BATL-2 instrument was identified as the most effective structured clinical review tool for detecting primary blast-related TBI.

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