Improved detection of local tumor progression after ablation or resection of colorectal liver metastases using [18F]FDG-PET/contrast-enhanced CT versus contrast-enhanced CT alone: results from a Dutch prospective cohort - Takeaways - MDSpire

Improved detection of local tumor progression after ablation or resection of colorectal liver metastases using [18F]FDG-PET/contrast-enhanced CT versus contrast-enhanced CT alone: results from a Dutch prospective cohort

  • By

  • O. D. Bijlstra

  • S. van Mossel

  • B. Boekestijn

  • M. C. Burgmans

  • E. L. van Persijn van Meerten

  • D. D. D. Rietbergen

  • S. Shahbazi Feshtali

  • R. J. Swijnenburg

  • F. H. P. van Velden

  • H. Koffijberg

  • L. F. de Geus-Oei

  • J. S. D. Mieog

  • July 11, 2026

  • 0 min

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  • 1

    Colorectal cancer is the most common gastrointestinal malignancy, with the liver as the primary site of metastases in 30%-50% of patients.

  • 2

    Current imaging practices for evaluating tumor progression after treatment include contrast-enhanced CT and serum CEA, but have limitations in accuracy.

  • 3

    Adding [18F]FDG-PET/CT to CECT may improve tumor detection by revealing metabolic activity that is not visible on morphological imaging alone.

  • 4

    The study analyzed the diagnostic value of [18F]FDG-PET/CT in patients with colorectal liver metastases following thermal ablation or resection.

  • 5

    The first follow-up imaging after local treatment was conducted 3-5 months later, combining CECT with [18F]FDG-PET/CT to assess recurrence.

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